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68Munjal A, Hanezzo E, Mitchison TJ, Megason SG. (2020). “Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis”, Cell, in press.bioRxivBio
67Knudsen TB, Spielmann M, Megason SG, Faustman EM. (2021). “Single‐cell profiling for advancing birth defects research and prevention”, Birth Defects Res, doi: 10.1002/bdr2.1870linkBio
66Tsai T, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg CP*, Megason SG*. (2020). “An adhesion code ensures robust pattern formation during tissue morphogenesis”, Science, 370(6512) bioRxivBio
65Mosaliganti KR, Swinburne IA, Chan CU, Obholzer ND, Green AA, Tanksale S, Mahadevan L*, Megason SG*. (2019). “Size Control of the Inner Ear Via Hydraulic Feedback”, eLife, 8:e39596linkBio
64O’Brown N, Megason SG*, Gu C*. (2019). “Suppression of transcytosis regulates zebrafish blood-brain barrier function”, eLife, 8:e47326.linkBio
63O’Brown ZK, Boulias K, Wang J, Wang SY, O’Brown NM, Hao Z, Shibuya H, Fady PE, Shi Y, He C, Megason SG, Liu T, Greer EL. (2019). “Sources of artifact in measurements of 6mA and 4mC abundance in eukaryotic genomic DNA”, BMC Genomics. 20(1):445linkBio
62Ishimatsu K, Cha A, Collins ZM, Megason SG. (2019). “Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling”, J. Vis. Exp. (147), e59434linkBio
61Collins ZM, Ishimatsu K, Tsai T, Megason SG. (2018). “A Scube2-Shh feedback loop links morphogen release to morphogen signaling to enable scale invariant patterning of the ventral neural tube”, bioRxiv.bioRxivBio
60Megason SG (2018). “Train – Code Visually” A completely visual programming language for teaching anyone how to code.web appEng
59Xiong F, Tentner AR, Hiscock TH, Huang P, Megason SG (2018), “Heterogeneity of Sonic Hedgehog Response Dynamics and Fate Specification in Single Neural Progenitors”, bioRxiv.bioRxivBio
58Gao R, Asano SM, Upadhyayula S, Pisarev I, Milkie DE, Liu TL, Singh V, Graves A, Huynh GH, Zhao Y, Bogovic J, Colonell J, Ott CM, Zugates C, Tappan S, Rodriguez A, Mosaliganti KR, Megason SG, Lippincott-Schwartz J, Hantman A, Rubin GM, Kirchhausen T, Saalfeld S, Aso Y, Boyden ES*, Betzig E*. (2018). “Cortical Column and Whole Brain Imaging of Neural Circuits with Molecular Contrast and Nanoscale Resolution”, Science, 363 (6424).linkBio
57Swinburne IA, Mosaliganti KR, Upadhyayula S, Liu TL, Hildebrand DGC, Tsai T, Chen A, Al-Obeidi E, Fass A, Malhotra S, Engert E, Lichtman JW, Kirchhausen T, Betzig E, Megason SG. (2018). “Lamellar Barriers In The Endolymphatic Sac Act As A Relief Valve To Regulate Inner Ear Pressure”, eLife, 7:e37131linkBio
56Ishimatsu K, Hiscock TW, Collins ZM, Sarib DWK, Lischer K, Richmond DL, Bessho Y, Matsui T, Megason SG. (2018). “Size-reduced embryos reveal a gradient scaling based mechanism for zebrafish somite formation”, Development 145(11)linkhighlightinterviewBio
55Hiscock TW, Miesfeld JB, Mosaliganti KR, Link BA, Megason SG. (2018). “Feedback between tissue packing and neurogenesis in the zebrafish neural tube”, Development 145(9).pdfcoverprelightBio
54Briggs JA, Weinreb C, Wagner DE, Megason SG, Peshkin L, Kirschner MW*, Klein AM*. (2018). “The dynamics of gene expression in vertebrate embryogenesis at single cell resolution”, Science, 360(6392):eaar5780pdfBio
53Wagner DE, Weinreb C, Collins ZM, Briggs JA, Megason SG*, Klein AM*. (2018). “Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo”, Science 360(6392):981-987.pdfcover Science previewScience perspective Nature previewBio
52Liu YL, Upadhyayula S, Milkie DE, Singh V, Wang K, Swinburne IA, Mosaliganti KR,Collins ZM, Hiscock TW, Shea J, Kohrman AQ, Medwig TN, Dambournet D, Forster R, Cunniff B, Ruan Y, Yashiro H, Scholpp S, Meyerowitz EM, Hockemeyer D, Drubin DG, Martin BL, Matus DQ, Koyama M, Megason SG, Kirchhausen T, Betzig E. (2018). “Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms”, Science, Apr 20;360(6386). pii: eaaq1392. doi: 10.1126/science.aaq1392.pdfcoverBio
51Megason SG. (2018). “Dynamic Encoding in the Notch Pathway”, Dev Cell 44:411linkPreview
50Green AA, Mosaliganti KR, Swinburne IA, Obholzer ND, Megason SG. (2017). “Recovery of shape and size in a developing organ pair” Developmental Dynamics 246(6):451-465.pdfBio
49Aguet F, Upadhyayula S, Gaudin R, Chou YY, Cocucci E, He K, Chen BC, Mosaliganti K, Pasham M, Skillern W, Legant W, Liu TL, Findlay G, Marino E, Danuser G, Megason SG, Betzig E, Kirchhausen T. (2016). “Membrane dynamics of dividing cells imaged by lattice light sheet microscopy”. Mol Biol Cell Aug 17.pdfBio
48Nissim S, Weeks O, Talbot JC, Hedgepeth JW, Wucherpfennig J, Schatzman-Bone S, Swinburne I, Cortes M, Alexa K, Megason S, North TE, Amacher SL, Goessling W. (2016). “Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development.” Dev Biol. 418(1):108-23.pdfBio
47Lee SG, Huang M, Obholzer ND, Sun S, Li W, Petrillo M, Dai P, Zhou Y, Cotanche DA, Megason SG, Li H, Chen ZY. (2016). “Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration”, PLoS One 11(6):e0157768.pdfBio
46Hiscock TW, Megason SG. (2015). “Orientation of Turing-like Patterns by Morphogen Gradients and Tissue Anisotropies”, Cell Systems 1(6), 408-416.pdfBio
46Swinburne IA, Mosaliganti KR, Green AA, Megason SG. (2015). “Improved long-term imaging of embryos with genetically encoded α-bungarotoxin”, PLOS ONE 10(8):e0134005pdfBio
45Xiong F, Megason SG. (2015). “Abstracting the principles of development using imaging and modeling”, Integrative Biology, 7, 633 – 642pdfBio
44Xiong F, Obholzer ND, Noche RR, Megason SG. (2015). “Multibow: Digital Spectral Barcodes for Cell Tracing”, PLOS ONE 10(5):e0127822.pdfBio
43Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT (2015). “Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin”, Development 142, 1137-45pdfBio
42Hiscock TW, Megason SG. (2015). “Mathematically guided approaches to distinguish models of periodic patterning”, Development 142, 409-419.pdfBio
41Xiong F, Ma W, Hiscock TW, Mosaliganti KR, Tentner AR, Brakke KA, Rannou N, Gelas A, Souhait, Swinburne IA, Obholzer ND, Megason SG. (2014). “Interplay of cell shape and division orientation promotes robust morphogenesis of developing epithelia.” Cell, 159(2):415-427.pdfcodeBio
40Mosaliganti KR, Gelas A, Megason SG. (2013). “An efficient, scalable, and adaptable framework for solving generic systems of level-set PDEs”, Frontier in Neuroinformatics 7:35. PMID: 24501592 .pdfEng
39Xiong F, Tentner AR, Huang P, Gelas A, Mosaliganti KR, Souhait L, Rannou R, Swinburne IA, Obholzer ND, Cowgill PD, Schier AF, Megason SG (2013). “Specified Neural Progenitors Sort to Form Sharp Domains after Noisy Shh Signaling” , Cell, 153(3):550-561.pdfPreviewPaperFlickF1000Bio
38Miller AC, Obholzer ND, Shah AN, Megason SG, Moens CB. (2013). “RNA-seq based mapping and candidate identification of mutations from forward genetic screens”. Genome Res. 23(4):679-86pdfBio
37Mosaliganti KR, Noche RR, Xiong F, Swinburne IA, Megason SG. (2012). “ACME: Automated Cell Morphology Extractor for Comprehensive Reconstruction of Cell Membranes”. PLoS Comput Biol 8(12):e1002780pdfEng
36Obholzer N*, Swinburne IA*, Schwab E, Nechiporuk AV, Nicolson T, Megason SG (2012). “Rapid Positional Cloning of Zebrafish Mutations by Linkage and Homozygosity Mapping Using Whole Genome Sequencing.” Development 139, 4280-4290pdfBio
35Shaheen R, Faqeih E, Shamseldin HE, Noche RR, Sunker A, Alshammari MJ, Al-Sheddi T, Adly N, Al-Dosari MS, Megason SG, Al-Husain M, Al-Mohanna F, Alkuraya FS. (2012). “POC1A Truncation Mutation Causes a Ciliopathy in Humans Characterized by Primordial Dwarfism.”, Am J Hum Genet 91(2):330-6. PMID: 22840364pdfBio
34Huang P, Xiong F, Megason SG, Schier AF. (2012). “Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord.” PLoS Genet. 8(6):e1002762. PMID: 22685423pdfBio
33Xu C, Fan ZP, Müller P, Fogley R, Dibiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. (2012). “Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway.” Dev Cell. 22(3):625-38.pdfBio
32Trinh LA, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, Jayasena CS, Saxena A, Hawk R, Gonzalez-Serricchio A, Dixson A, Chow E, Gonzales C, Leung HY, Solomon I, Bronner-Fraser M, Megason SG, and Fraser SE. (2011). “A versatile gene trap to visualize and interrogate the function of the vertebrate proteome”, Genes and Development 25:2306-2320PMID 22056673pdfBio
31Megason SG, Srinivas S, Dickinson ME, Hadjantonakis AK. (2011). “Editorial Overview – Microscopy to mechanism across the scales of development”, Current Opinions in Genetics and Development 21:1-5 PMID 21996420pdfBio
30Wühr M, Obholzer ND, Megason SG, Detrich HW 3rd, Mitchison TJ. (2011). “Live imaging of the cytoskeleton in early cleavage-stage zebrafish embryos.” Methods Cell Biol. 101:1-18. PMID:21550437pdfBio
29Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. (2011). “Towards a synthetic chloroplast.” PLoS One 6(4):e18877. PMID: 21533097pdfBio
28Schwab E, Gelas A, Souhait L, Rannou N, Mosaliganti K, Megason S. (2011). “CTest Integration of Sikuli Automated GUI Testing” The MIDAS Journal.pdfEng
27Mosaliganti KR, Janoos F, Gelas A, Noche R, Obholzer N, Machiraju R, Megason SG. (2010). “Anisotropic Plate Diffusion Filtering for Detection of Cell Membranes in 3D Microscopy Images”. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2010. ISBI ’10, pp. 588-591.pdfEng Conf
26Perrot-Audet A.; Mosaliganti K.; Gelas A.; Rannou N.; Souhait L.; Megason S. (2010). “A simple Qt based comparison program for ITK and VTK images.” Insight Journal.pdfEng
25Megason SG. (2009). “In toto imaging of embryogenesis with confocal time-lapse microscopy”. Methods Mol Biol. 546:317-32.pdfBio
24Mosaliganti K.; Gelas A.; Megason S. (2009). “An Adaptive Thresholding Image Filter” Insight Journal.pdfEng
23Mosaliganti KR, Gelas A, Gouaillard A, Megason SG. (2009) “Microscopy Image Analysis: Blob Segmentation using Geodesic Active Contours”. Insight Journal.pdfEng
22Mosaliganti KR, Smith B, Gelas A, Gouaillard A, Megason SG (2009) “Cell Tracking using Coupled Active Surfaces for Nuclei and Membranes”. Insight Journal.pdfEng
21Mosaliganti KR, Gelas A, Gouaillard A, Megason SG. (2009) “Level Set Segmentation Using Coupled Active Surfaces”. Insight Journal.pdfEng
20Mosaliganti KR, Smith B, Gelas A, Gouaillard A., Megason SG (2009) “Level Set Segmentation: Active Contours Without Edges”. Insight Journal.pdfEng
19Mosaliganti KR, Gelas A, Cowgill P, Megason SG (2009) “An Optimized N-Dimensional Hough Filter for Detecting Spherical Image Objects”. Insight Journal.pdfEng
18Gelas A, Gouaillard A, Megason SG. (2009) “Surface Mesh Smoothing”. Insight Journal.pdfEng
17Mosaliganti KR, Gelas A, Megason SG (2009) “An Adaptive Thresholding Image Filter”. Insight Journal.pdfEng
16Gelas A, Mosaliganti KR, Gouaillard A, Souhait L, Noche RR, Obholzer ND, Megason SG. (2009) “Variational Level-Set with Gaussian Shape Model for Cell Segmentation” In IEEE International Conference on Image Processing (ICIP’09)’s Proceedings, pp.1089-1092.pdfEng Conf
15Gouaillard A, Mosaliganti KR, Gelas A, Souhait L, Obholzer ND, Megason SG (2009) “Streaming Level Set Algorithm for 3D Segmentation of Confocal Microscopy” International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’09)’s Proceedings, pp.3621-3624.pdfEng Conf
14Mosaliganti KR, Gelas A, Gouaillard A, Noche RR, Obholzer ND, and Megason SG (2009) “Detection of Spatially Correlated Objects in 3D Images using Appearance Models and Coupled Active Contours”. Proceedings of Conference on Medical Image Computing and Computer-Assisted Interventions (MICCAI 2009), volume 5762/2009, pp.641-648, PMID 20426166pdfEng Conf
13Mosaliganti KR, Gelas A, Gouaillard A, and Megason SG (2009) “Tissue Level Segmentation and Biological Structures in Microscopic Images Based on Density Maps”. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009. ISBI ’09, pp.1354 – 1357.pdfEng Conf
12Gelas A, Gouaillard A, Megason SG. (2008) “Mutable Priority Queue Container”. Insight Journal.pdfEng
11Gelas A, Gouaillard A, Megason SG. (2008) “Surface Mesh Discrete Curvature Estimators”. Insight Journal.pdfEng
10Gelas A, Gouaillard A, Megason SG. (2008) “Surface Mesh Normals Filter”. Insight Journal.pdfEng
9Gelas A, Gouaillard A, Megason SG. (2008) “Surface Mesh Incremental Decimation Framework”. Insight Journal.pdfEng
8Gelas A, Gouaillard A, Megason SG. (2008) “Triangular Mesh Delaunay Conforming Filter”. Insight Journal.pdfEng
7Megason SG, Fraser SE. (2007). “Imaging in Systems Biology”. Cell, 130:784-795.pdfBio
6Link BA, Megason SG. (2007) “Zebrafish as a model for development”, in Sourcebook of Models for Biomedical Research, edited by Conn, PM. Humana Press, ISBN: 978-1-58829-933-8.pdfBio
5Cedilnik A, Baumes J, Ibanez L, Megason S, Wylie B. (2007). “Integration of information and volume visualization for analysis of cell lineage and gene expression during embryogenesis”. Proceedings of SPIE Vol. #6809.pdfEng Conf
4Gouaillard A, Brown T, Bronner-Fraser M, Fraser SE, Megason SG. (2007). “GoFigure and The Digital Fish Project: Open tools and open data for an imaging based approach to system biology”. Insight Journal – special edition “2007 MICCAI Open Science Workshop”.pdfEng Conf
3Megason SG, Amsterdam A, Hopkins N, LinS. (2006). “Uses of GFP in Transgenic Vertebrates” in Green Fluorescent Protein: Properties, Applications and Protocols, Second Edition, Edited by Martin Chalfie and Steven R. Kain. Wiley Press.pdfBio
2Megason SG, Fraser SE. (2003) “Digitizing life at the level of the cell: high-performance laser-scanning microscopy and image analysis for in toto imaging of development.” Mech Dev. 2003 Nov;120(11):1407-20.pdfBio
1Megason SG, McMahon AP. (2002) “A mitogen gradient of dorsal midline Wnts organizes growth in the CNS”. Development. 2002 May;129(9):2087-98.pdfBio
0Megason SG. (2001) A mitogen gradient of dorsal midline Wnts organizes growth in the CNS, PhD Thesis, Department of Molecular and Cellular Biology, Harvard University.pdfBio